Prof. Dr. Ahmet Gökhan AKKAN

Yayın Ağı

Makaleler 55

1. Exploring the Modulatory Effects of Vitamin B12 on Morphine-Induced Conditioned Place Preference in Rats

Uskur T., Taşdemir F. Ü., Öztürk M. A., Sönmez H., TODURGA SEVEN Z. G., Gökdemir S., et al.

Psychiatry and Clinical Psychopharmacology , cilt.35, sa.3, ss.269-274, 2025 (SCI-Expanded, Scopus, TRDizin)

2. Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway

Sonmez M. I., Bukharı A., Kose C., Sonmez H., Özyazgan S., Akkan A. G.

FRONTIERS IN PHARMACOLOGY , cilt.13, 2022 (SCI-Expanded, Scopus)

3. The Prevalence of Potential Drug-Drug Interactions in CKD-A Retrospective Observational Study of Cerrahpasa Nephrology Unit

BUKHARI A., Sonmez I., Kose C., OKTAN B., Alagoz S., Sonmez H., et al.

MEDICINA-LITHUANIA , cilt.58, sa.2, 2022 (SCI-Expanded, Scopus)

4. Investigation of the pharmacological potential of myricetin on alcohol addiction in mice

Yunusoglu O., BUKHARI A., Turel C. A., Demirkol M. H., Berköz M., AKKAN A. G.

JOURNAL OF RESEARCH IN PHARMACY , cilt.26, sa.4, ss.722-733, 2022 (ESCI, Scopus, TRDizin)

5. TNF-α ile Oluşturulan in Vitro İnsan Safen ven Ateroskleroz Modelinde Atorvastatin ve Pitavastatinin Matriks Metalloproteinaz 2 Üzerine Etkilerinin Karşılaştırılması

Özen D., Önal B., Gezen Ak D., Dursun E., Akkan A. G.

Ege Klinikleri Tıp Dergisi , cilt.59, sa.2, ss.175-181, 2021 (TRDizin) Sürdürülebilir Kalkınma

6. Effect of Three PDEIs on Neuroprotective and Autophagy Proteins in vitro AD Model

Saygisever-Faikoglu K., Faikoglu G., Celik H., Ugur S. A., AKKAN A. G., Kelicen-Ugur P., et al.

INTERNATIONAL JOURNAL OF PHARMACOLOGY , cilt.17, sa.4, ss.169-179, 2021 (SCI-Expanded)

7. The Effect of Orphenadrine on Rewarding Property of Morphine-Induced Conditioned Place Preference

Köse Ç., Bukharı A., Akkan A. G., Özyazgan S.

Cerrahpaşa Tıp Dergisi , cilt.44, sa.2, ss.80-85, 2020 (TRDizin)

8. Investigation of the roles of new antiepileptic drugs’ and serum BDNF levels in efficacy and safety monitoring and quality of life: a clinical research

Demir M., Akarsu E. O., Dede H. Ö., Bebek N., Yıldız S. Ö., Baykal B., et al.

Current Clinical Pharmacology , cilt.15, sa.1, ss.49-63, 2020 (ESCI, Scopus)

9. The Anti-Inflammatory Effects of Anacardic Acid on a TNF-alpha Induced Human Saphenous Vein Endothelial Cell Culture Model

Onal B., Ozen D., Demir B., Ak D. G., Dursun E., Demir C., et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY , cilt.21, ss.710-719, 2020 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

10. Receptor for advanced glycation end products gene polymorphisms in cardiac syndrome X

Onal B., Ozen D., Demir B., Akkan A. G., Ozyazgan S.

BIOMEDICAL REPORTS , cilt.11, sa.3, ss.123-129, 2019 (ESCI, Scopus)

11. The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

Demir B., Onal B., Ozyazgan S., Demir E., Bakuy V., Akkan A. G.

CARDIOVASCULAR THERAPEUTICS , 2019 (SCI-Expanded, Scopus)

12. Investigation of MTHFR gene C677T polymorphism in cardiac syndrome X patients

Kandaz C., Onal B., Ozen D., Demir B., Akkan A. G., Ozyazgan S.

JOURNAL OF CLINICAL LABORATORY ANALYSIS , cilt.32, sa.2, 2018 (SCI-Expanded, Scopus)

13. Effects of propofol on conditioned place preference in male rats: Involvement of nitrergic system

Shahzadi A., Uskur T., AKKAN A. G., Çevreli B., UZBAY İ. T.

AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE , cilt.44, sa.2, ss.167-174, 2018 (SCI-Expanded, SSCI, Scopus)

14. Plasma Betatrophin Levels of Subjects Classified with Normal, Impaired, and Diabetic Glucose Tolerance, and Subjects with Impaired Fasting Glucose

Ozyazgan S., Onal B., Kurtulus E. M., UZUN H., Akkan G., KONUKOĞLU D.

HORMONE AND METABOLIC RESEARCH , cilt.49, sa.6, ss.434-439, 2017 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

15. Does Inflammation Have a Role in the Pathogenesis of Cardiac Syndrome X? A Genetic-Based Clinical Study With Assessment of Multiple Cytokine Levels

Demir B., Onal B., Ozyazgan S., Kandaz C., UZUN H., Aciksari G., et al.

ANGIOLOGY , cilt.67, sa.4, ss.355-363, 2016 (SCI-Expanded, Scopus)

16. Dexmedetomidine induces conditioned place preference in rats: Involvement of opioid receptors

Uskur T., Barlas M. A., Akkan A. G., Shahzadi A., Uzbay T.

BEHAVIOURAL BRAIN RESEARCH , cilt.296, ss.163-168, 2016 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

17. The Effects of Potassium Channels in Human Internal Mammary Artery

Afsar S., Hemsinli D., Ozyazgan S., Akkan A. G., Arslan C.

PHARMACOLOGY , cilt.97, ss.72-77, 2016 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

18. Delta(9)-tetrahydrocannabinol treatment improved endothelium-dependent relaxation on streptozotocin/nicotinamide-induced diabetic rat aorta

Altinok A., Coskun Z. M., Karaoglu K., BOLKENT Ş., Akkan A. G., Ozyazgan S.

ACTA PHYSIOLOGICA HUNGARICA , cilt.102, sa.1, ss.51-59, 2015 (SCI-Expanded, Scopus)

19. Cardiac Troponin-I (cTnI) a Biomarker of Cardiac Injuries Induced by Doxorubicin Alone and in Combination with Ciprofloxacin, Following Acute and Chronic Dose Protocol in Sprague Dawley Rats

Shahzadi A., Sonmez I., Allahverdiyev O., Onal B., Kandaz C., Ozyazgan S. O., et al.

INTERNATIONAL JOURNAL OF PHARMACOLOGY , cilt.10, sa.5, ss.258-266, 2014 (SCI-Expanded, Scopus)

20. The in vitro Effects of Iloprost with Other Vasodilators on the Human Internal Thoracic Artery

Cantürk E., ARSLAN C., ALTıNOK A., ÖZYAZGAN S., BESIRLI K., BOZKURT A., et al.

ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY , cilt.16, sa.2, ss.78-84, 2010 (SCI-Expanded, Scopus)

21. The role of mast cells in the genesis of acute manifestations following the intravenous injection of meperidine in dogs

ALAADDİN A., YILLAR D. O., AKKAN A. G., KÜÇÜKHÜSEYİN C.

J Basic Clin Physiol Pharmacol. , cilt.1, sa.20, ss.67-72, 2009 (Hakemli Dergi)

22. The effect of oral and subcutaneous meperidine on the maximal electroshock seizure (mes) in mice

Yillar D., Akkan A. G., Akcasu A., Özüner Z., Eşkazan E., Küçükliüseyin C.

Journal of Basic and Clinical Physiology and Pharmacology , cilt.20, sa.2, ss.159-168, 2009 (Scopus)

23. The effects of 5-aminoimidazole-4-carboxamide riboside on the pancreas in neonatal streptozotocin-diabetic rats

ÖZTÜRK SEZGİN M., Bolkent S., Kaya-Dagistanli F., TUNÇDEMİR M., Yilmazer S., Akkan A. G.

ACTA DIABETOLOGICA , cilt.43, sa.3, ss.61-65, 2006 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

24. Effect of glucagon-like peptide-1(7-36) and exendin-4 on the vascular reactivity in streptozotocin/nicotinamide-induced diabetic rats

Ozyazgan S., Kutluata N., Afsar S., Ozdas S., Akkan A. G.

PHARMACOLOGY , cilt.74, sa.3, ss.119-126, 2005 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

25. Comparison of rational pharmacotherapy decision-making competence of general practitioners with intern doctors

Akici A., Kalaca S., Goren M., Akkan A. G., KARAALP A., Demir D., et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY , cilt.60, sa.2, ss.75-82, 2004 (SCI-Expanded, Scopus)

26. The effect of agmatine on the vascular reactivity in streptozotocin-diabetic rats

Ozyazgan S., Bicakci B., ÖZAYDIN A., Denizbasi A., Unluer E., Akkan A. G.

PHARMACOLOGICAL RESEARCH , cilt.48, sa.2, ss.133-138, 2003 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

27. Role of bombesin and cholecystokinin receptors in gastric injury induced by hemorrhagic shock in the rat

Unluer E., Denizbasi A., Ozyazgan S., Akkan A. G.

PHARMACOLOGY , cilt.68, sa.2, ss.74-80, 2003 (SCI-Expanded, Scopus)

28. Low cost antibiotic loaded systems for developing countries

HEYBELİ N., OKTAR F., ÖZYAZGAN S., AKKAN A. G., ÖZSOY S.

Technol Health Care. , cilt.3, sa.11, ss.207-216, 2003 (Hakemli Dergi)

29. Effect of hyperoxia and metformin on vascular responses to vasoactive compounds in rats

Ozyazgan S., Senses V., Akkan A. G., Ince E., Sultuybek G.

Journal of Basic and Clinical Physiology and Pharmacology , cilt.12, sa.3, ss.249-262, 2001 (Scopus) Sürdürülebilir Kalkınma

30. Effect of 5-aminoimidazole-4-carboxamide riboside (aica-r) on isolated thoracic aorta responses in streptozotocin-diabetic rats

Senses V., Ozyazgan S., İNCE E. Z., TUNÇDEMİR M., Kaya F., ÖZTÜRK SEZGİN M., et al.

Journal of Basic and Clinical Physiology and Pharmacology , cilt.12, sa.3, ss.227-248, 2001 (Scopus) Sürdürülebilir Kalkınma

31. Lidocaine 10% in the endotracheal tube cuff: blood concentrations, haemodynamic and clinical effects

Altintas F., Bozkurt P., Kaya G., Akkan G.

EUROPEAN JOURNAL OF ANAESTHESIOLOGY , cilt.17, sa.7, ss.436-442, 2000 (SCI-Expanded, Scopus)

32. Impaired relaxation in aorta from streptozotocin-diabetic rats: Effect of aminoguanidine (AMNG) treatment

Özyazgan S., Unlucerci Y., Bekpinar S., Akkan A. G.

Experimental Diabesity Research , cilt.1, sa.2, ss.145-153, 2000 (SCI-Expanded, Scopus)

33. The effect of succinic acid monomethyl ester (SAM) on the responses of isolated thoracic aorta in STREPTOZOTOCIN-DIABETIC rats

Ozyazgan S., Senses V., Ince E., Sultuybek G., Utkan T., Akkan A. G.

PHARMACOLOGICAL RESEARCH , cilt.38, sa.1, ss.73-79, 1998 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

34. The effect of isradipine on maximal electroshock seizures in mice

Ozyazgan S., Senses V., Utkan T., Yildiran G., ULAK G., Gacar N., et al.

GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM , cilt.31, sa.1, ss.133-135, 1998 (SCI-Expanded, Scopus)

35. Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor of the uninflamed human eye

Akkan A. G., Mutlu I., Ozyazgan S., Gok A., Yigit U., Ozuner Z., et al.

JOURNAL OF CHEMOTHERAPY , cilt.9, sa.4, ss.257-262, 1997 (SCI-Expanded, Scopus)

36. Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes

Akkan A. G., Mutlu I., Özyazgan S., Gök A., Yigit U., Özüner Z., et al.

International Journal of Clinical Pharmacology and Therapeutics , cilt.35, sa.5, ss.214-217, 1997 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

37. Quantification of Ofloxacin in Biological Fluids by High-Performance Liquid Chromatography

Özyazgan S., şenses V., Özüner Z., Akkan A. G.

Journal of Basic and Clinical Physiology and Pharmacology , cilt.8, ss.73-80, 1997 (Scopus)

38. STANDARDIZED PROCEDURE FOR THE ASSAY AND IDENTIFICATION OF HYPOGLYCEMIC SULFONYLUREAS IN HUMAN PLASMA

SENER A., AKKAN A. G., MALAISSE W.

ACTA DIABETOLOGICA , cilt.32, sa.1, ss.64-68, 1995 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

39. STANDARDIZED PROCEDURE FOR THE IDENTIFICATION AND ASSAY OF HYPOGLYCEMIC SULFONYLUREAS IN HUMAN PLASMA

AKKAN A. G., SENER A., MALAISSE W.

DIABETOLOGIA , cilt.37, 1994 (SCI-Expanded, Scopus)

40. Insulinotropic action of AICA riboside. I. Insulin release by isolated islets and the perfused pancreas.

Akkan A. G., Malaisse W.

Diabetes research (Edinburgh, Lothian) , cilt.25, sa.1, ss.13-23, 1994 (SCI-Expanded)

41. Iterative pulse administration of succinic acid monomethyl ester to streptozotocin diabetic rats.

Akkan A. G., Malaisse W.

Diabetes research (Edinburgh, Lothian) , cilt.23, sa.2, ss.55-63, 1993 (SCI-Expanded) Sürdürülebilir Kalkınma

42. Protective effect of succinic acid monomethylester against streptozotocin-induced diabetes mellitus

Akkan A. G., Malaisse W.

Medical Science Research , cilt.21, sa.12, ss.467, 1993 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

43. The effect of metoprolol on maximal electroshock seizure in the mice

Ozyazgan S., Ozuner Z., Akkan A. G., Tekinsen S.

Cerrahpasa Tip Fakultesi Dergisi , cilt.23, sa.1, ss.9-14, 1992 (Scopus)

44. The effects of 4-aminopyridine (4-AP) on the insulin secretion in isolated perfused canine pancreas

Akkan A. G., Ozuner Z., Kaptanoglu Z., Hatemi H., Gundogdu S., Demiroglu C.

Cerrahpasa Tip Fakultesi Dergisi , cilt.23, sa.1, ss.21-28, 1992 (Scopus)

45. PRESERVATION OF THE ANOMERIC SPECIFICITY OF GLUCOSE-INDUCED INSULIN RELEASE IN PARTIALLY PANCREATECTOMIZED RATS

LECLERCQMEYER V., MALAISSELAGAE F., COULIC V., AKKAN A. G., MARCHAND J., MALAISSE W.

DIABETOLOGIA , cilt.35, sa.6, ss.505-509, 1992 (SCI-Expanded, Scopus)

46. Effects of glimepiride and glibenclamide on insulin and glucagon secretion by the perfused rat pancreas

Leclercq-Meyer V., Akkan A. G., Marchand J., Malaisse W.

Biochemical Pharmacology , cilt.42, sa.8, ss.1634-1637, 1991 (SCI-Expanded, Scopus)

47. The influence of choline ascorbate on the blood levels of ascorbic acid in humans

Yillar D., Akkan A. G., Akcasu A., Azuner Z.

International Journal of Clinical Pharmacology Therapy and Toxicology , cilt.29, sa.6, ss.228-230, 1991 (Scopus)

48. The effect of verapamil (D-365) on the insulin secretion in isolated dog pancreas

Hatemi H., Akkan A. G., Kaptanoglu Z., Ozuner Z., Gundogdu S., Demiroglu C.

Cerrahpasa Tip Fakultesi Dergisi , cilt.21, sa.2, ss.167-170, 1990 (Scopus)

49. The effect of nitrendipine (BAY e 5009) on insulin secretion in perfused isolated dog pancreas

Akkan A. G., Kaptanoglu Z., Ozuner Z., Hatemi H., Gundogdu S., Demiroglu C.

Cerrahpasa Tip Fakultesi Dergisi , cilt.21, sa.2, ss.175-178, 1990 (Scopus)

50. The effect of naloxone on the maximal electroshock seizures in mice

Eskazan E., Yillar D., Akcasu A., Akkan A. G.

Cerrahpasa Tip Fakultesi Dergisi , cilt.21, sa.2, ss.179-186, 1990 (Scopus)

51. The effect of diltiazem on insulin secretion in perfused isolated dog pancreas

Kaptanoglu Z., Akkan A. G., Ozuner Z., Hatemi H., Gundogdu S., Demiroglu C.

Cerrahpasa Tip Fakultesi Dergisi , cilt.21, sa.2, ss.171-174, 1990 (Scopus)

52. The effect of meperidine administered subcutaneously on maximal electroshock seizure in the mice

Yillar D., Akkan A. G., Akcasu A., Ozuner Z., Eskazan E.

Cerrahpasa Tip Fakultesi Dergisi , cilt.20, sa.4, ss.385-390, 1989 (Scopus)

53. The effect of propranolol on maximal electroshock seizures in mice

Akkan A. G., Yillar D., Eskazan E., Akcasu A., Ozuner Z.

International Journal of Clinical Pharmacology Therapy and Toxicology , cilt.27, sa.5, ss.255-257, 1989 (SCI-Expanded)

54. The effect of naloxone on the blood level of morphine and histamine in morphine perfused dogs

Akkan A. G., Akcasu A., Yillar D.

International Journal of Clinical Pharmacology Therapy and Toxicology , cilt.26, sa.12, ss.594-596, 1988 (SCI-Expanded)

55. The effect of naloxone on the blood levels of morphine and histamine in morphine dependent dogs

Akcasu A., Akkan A. G., Yillar D., Aksoy I.

International Journal of Clinical Pharmacology Therapy and Toxicology , cilt.26, sa.6, ss.317-319, 1988 (Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 13

1. Effect of denosumab on progesterone-treated luminal A breast cancer cells

Yenigün V. B., Beri E., Akkan A. G., Toluk Ö.

X. Multidisciplinary Cancer Research Congress, Eskişehir, Türkiye, 8 - 11 Mayıs 2025, (Özet Bildiri)

2. B12 VİTAMİNİNİN SIÇANLARDA MORFİNLE OLUŞTURULMUŞ KOŞULLANDIRILMIŞ YER TERCİHİ TESTİNDEKİ ETKİLERİNİN İNCELENMESİ

Uskur T., Taşdemir F. Ü., Öztürk A., Sönmez H., Todurga Seven Z. G., Faikoğlu G., et al.

26. ULUSAL ve 1. ULUSLARARASI FARMAKOLOJİ KONGRESİ, Ankara, Türkiye, 4 - 06 Kasım 2021, cilt.1, sa.56, ss.56-57, (Özet Bildiri)

3. Fruktoz ile hiperinsüliemi oluşturulmuş sıçanların aortunda meydana gelen vasküler değişiklikler üzerine THC’nın terapötik etkisi.

Todurga Seven Z. G., Çagla K., COŞKUN Z. M., Sönmez M. İ., AKKAN A. G., BOLKENT H. S., et al.

25. ULUsal Farmakoloji Kongresi, Türkiye, 4 - 07 Kasım 2019, (Özet Bildiri)

4. Investigation of MTHFR Gene C677T Polymorphism in Cardiac Syndrome X Patients

Kandaz C., ÖNAL B., ÖZEN D., Demir B., AKKAN A. G., ÖZYAZGAN S.

Innovation in Drug and Biotechnology, 11 - 13 Mayıs 2017, (Özet Bildiri)

5. Plasma Betatrophin Levels in Subjects With Normal or Impaired Glucose Tolerance Test

ÖZYAZGAN S., ÖNAL B., KURTULUŞ E., KONUKOĞLU D., AKKAN A. G., UZUN H.

Pathology and Laboratory Medicine: on the forefront of personalized medicine, WASPALM 2016, Cancun, Meksika, 18 - 21 Eylül 2016, cilt.1, ss.165, (Tam Metin Bildiri)