Current Clinical Pharmacology, vol.15, no.1, pp.49-63, 2020 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
Current Clinical Pharmacology
Epilepsy, new antiepileptic drugs, TDM, safety, QOLIE-31, BDNF, efficacy, NEUROTROPHIC FACTOR, PHARMACOKINETIC INTERACTIONS, ILAE-COMMISSION, BRAIN, EPILEPSY, LAMOTRIGINE, EMPLOYMENT, MECHANISM, SEIZURES
Objective: We aimed to determine the therapeutic drug monitoring (TDM) features and the relation to Brain-Derived Neurotrophic Factor (BDNF) of frequently used new antiepileptic drugs (NADs) including lamotrigine (LTG), oxcarbazepine (OXC), zonisamide (ZNS) and lacosamide (LCM). Moreover, we investigated their effect on the quality of life (QoL).