The effect of agmatine on the vascular reactivity in streptozotocin-diabetic rats

Ozyazgan S., Bicakci B., ÖZAYDIN A., Denizbasi A., Unluer E., Akkan A. G.

PHARMACOLOGICAL RESEARCH, vol.48, no.2, pp.133-138, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 2
  • Publication Date: 2003
  • Doi Number: 10.1016/s1043-6618(03)00101-4
  • Journal Name: PHARMACOLOGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.133-138
  • Bezmialem Vakıf University Affiliated: No

Abstract

Aim: We investigated the vascular effects of agmatine (decarboxylated arginine = AGM), an endogenous ligand for alpha(2)-adrenoceptors and imidazoline receptors, present in endothelium and smooth muscle, using the diabetic rat aortae.