The Anti-Inflammatory Effects of Anacardic Acid on a TNF-alpha Induced Human Saphenous Vein Endothelial Cell Culture Model

Onal B., Ozen D., Demir B., Ak D. G. , Dursun E., Demir C., ...More

CURRENT PHARMACEUTICAL BIOTECHNOLOGY, vol.21, pp.710-719, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21
  • Publication Date: 2020
  • Doi Number: 10.2174/1389201020666191105154619
  • Page Numbers: pp.710-719
  • Keywords: Coronary bypass, anacardic acid, saphenous vein, atherosclerosis, inflammation, NF-kappa B, NF-KAPPA-B, CORONARY-ARTERY-BYPASS, AMYLOID-BETA 1-42, ADHESION MOLECULES, ICAM-1 EXPRESSION, INDUCED VCAM-1, GRAFT, PATHOGENESIS, INHIBITION, ACTIVATION


Background and Objective: Coronary bypass operations are commonly performed for the treatment of ischemic heart diseases. Coronary artery bypass surgery with autologous human saphenous vein maintains its importance as a commonly used therapy for advanced atherosclerosis. Vascular inflammation-related intimal hyperplasia and atherosclerotic progress have major roles in the pathogenesis of saphenous vein graft disease.