Oxidative status and serum PON1 activity in beta-thalassemia minor

Selek S., ASLAN M., HOROZ M., GUR M., EREL O.

CLINICAL BIOCHEMISTRY, cilt.40, ss.287-291, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.clinbiochem.2006.10.028
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.287-291
  • Anahtar Kelimeler: beta-thalassemia minor, PON1, oxidative stress, total antioxidant capacity, LOW-DENSITY-LIPOPROTEIN, RED-BLOOD-CELLS, ANTIOXIDANT STATUS, XYLENOL ORANGE, PARAOXONASE, INHIBITION, SURVIVAL, CHILDREN, OXIDANT, LDL
  • Bezmiâlem Vakıf Üniversitesi Adresli: Hayır

Özet

Objectives: Paraoxonase-1 (PON1) deficiency is related to increased susceptibility to low density lipoprotein oxidation and development of atherosclerosis. The aim of this study was to investigate paraoxonase and arylesterase activities along with oxidative status parameters, and to find out if there is any increased susceptibility to atherogenesis, which might be reflected with increased oxidative stress and decreased serum PON1 activity in beta-thalassemia minor (BTM) subjects.