Nepetalactones and other constituents of Nepeta nuda ssp. albiflora

KOKDIL G., YALCIN S., Topcu G.

TURKISH JOURNAL OF CHEMISTRY, cilt.23, sa.1, ss.99-104, 1999 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 1999
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.99-104
  • Anahtar Kelimeler: Nepeta nuda ssp. albiflora, Lamiaceae, nepetalactones, dimeric 5,9-dehydronepetalactone, sesquiterpene, triterpenoids, steroids, STEREOCHEMISTRY, CATARIA
  • Bezmiâlem Vakıf Üniversitesi Adresli: Hayır

Özet

The hexane extract of Nepeta nuda ssp. albiflora led to the isolation of six known monoterpene nepetalactones, 4a alpha, 7 alpha,7a alpha-nepetalactone (1), 4a alpha, 7 beta,7a beta-nepetalactone (2), 4a beta,7 alpha,7a beta-nepetalactone (3), 4a beta,7 alpha,7a alpha-nepetalactone (4), 4a alpha,7 beta,7a beta-nepetalactone (5), 3 alpha-hydroxy-4a alpha,7 alpha,7a alpha-dihydronepetalactone (=nepetalic acid) (6) and a dimeric 5,9-dehydronepetalactone (7) along with two known steroids beta-sitosterol and sitosterol 3-one and a triterpene betulinic acid. The acetone extract of the same plant afforded compound 7 in a higher yield in addition to compounds 2 and 6, and sesquiterpene caryophyllene oxide, the iridoid glucoside 1,5,9-epideoxyloganic acid, the triterpenoids oleanolic, ursolic and betulinic acids, and sitosterol 3 beta-glucoside.