Association between interleukin-1 beta (IL-1 ss) gene polymorphism and outcome after head injury: an early report

Uzan M., Tanriverdi T., Baykara O., Kafadar A., Sanus G., Tureci E., ...More

ACTA NEUROCHIRURGICA, vol.147, no.7, pp.715-720, 2005 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 147 Issue: 7
  • Publication Date: 2005
  • Doi Number: 10.1007/s00701-005-0529-z
  • Journal Name: ACTA NEUROCHIRURGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.715-720
  • Bezmialem Vakıf University Affiliated: No

Abstract

Background. Recent studies focusing on the genetic influences on outcome after head injury (HI) have suggested that different alleles of certain genes are associated with different outcomes. Interleukin-1 beta (IL-1 beta) gene, especially beta 2 polymorphism, is frequently observed in Alzheimer's disease, a remarkable degenerative state in which HI is among the known risk factors. Therefore, the aim of this paper was to search for the possible association between the outcome and IL-1 beta gene polymorphism in human HI.