Effect of Quantitative and Semi-quantitative Elastography Methods for the Management of Borderline Lesions on Ultrasonography

Aksoy D. Ö., Yildiz S., Atasoy B., Alkan A., Kandemirli S. G., Cingöz M.

CURRENT MEDICAL IMAGING, vol.17, no.6, pp.767-774, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.2174/1573405616666201231102606
  • Journal Name: CURRENT MEDICAL IMAGING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.767-774
  • Keywords: Quantitative, semiquantitative, elastography, BI-RADS 4a, BI-RADS 3, borderline breast lesions, SHEAR-WAVE ELASTOGRAPHY, ULTRASOUND ELASTOGRAPHY, BREAST-LESIONS, STRAIN RATIO, CLINICAL-USE, BENIGN, DIFFERENTIATION, RECOMMENDATIONS, GUIDELINES, DIAGNOSIS
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Results: Except for the 13 BI-RADS 2 lesions, the remaining 180 lesions were biopsied. Pathology showed 83 lesions to be benign and 97 to be malignant. The sensitivity and specificity of the CUS were 96.9% and 75.0%, respectively with an accuracy of 86.0%. Cut-off points calculated based on ROC curves were 56.8 kPa for SWE, 3.53 for SWER and 3.81 for SER. When we downgraded BIRADS 4a lesions based on elastography results, the specificity (CUS+SER 96.9%, CUS+SWE 91.7%, and CUS+SWER 90.6%) and the accuracy (CUS+SER 95.3%, CUS+SWE 92.7%, and CUS+SWER 92.2%) were shown to be better than CUS. When we upgraded BI-RADS 3 lesions based on elastography results, the sensitivity of combined sets of SWE (99,0%) and SWER