Evaluation of the possible protective role of naringenin on gentamicin-induced ototoxicity: A preliminary study


Kocak I., Sarac S., Aydogan E., SENTURK E. , AKAKIN D., KÖROĞLU K., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.100, pp.247-253, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 100
  • Publication Date: 2017
  • Doi Number: 10.1016/j.ijporl.2017.07.008
  • Title of Journal : INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Page Numbers: pp.247-253
  • Keywords: Naringenin, Gentamicin, Ototoxicity, TUNEL, Auditory brainstem responses, Otoacoustic emission, Oxidative status, Anti-oxidative status, INDUCED NEPHROTOXICITY, INTRATYMPANIC GENTAMICIN, MENIERES-DISEASE, NITRIC-OXIDE, HAIR-CELLS, RATS, PREVENTION, ANTIOXIDANT, MODEL, INFLAMMATION

Abstract

Objectives: The purpose of this study is to evaluate the possible protective role of naringenin in gentamicin-induced ototoxicity through an audiological, biochemical and histopathological evaluation.