Evaluation of the possible protective role of naringenin on gentamicin-induced ototoxicity: A preliminary study

Kocak, I.; Sarac, S.; Aydogan, E.; SENTURK, EROL; AKAKIN, DİLEK; KÖROĞLU, KEMALETTİN; Ozer, Ömer

doi:10.1016/j.ijporl.2017.07.008

Evaluation of the possible protective role of naringenin on gentamicin-induced ototoxicity: A preliminary study

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Kocak I., Sarac S., Aydogan E., SENTURK E., AKAKIN D., KÖROĞLU K., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.100, pp.247-253, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 100
Publication Date: 2017
Doi Number: 10.1016/j.ijporl.2017.07.008
Journal Name: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.247-253
Keywords: Naringenin, Gentamicin, Ototoxicity, TUNEL, Auditory brainstem responses, Otoacoustic emission, Oxidative status, Anti-oxidative status, INDUCED NEPHROTOXICITY, INTRATYMPANIC GENTAMICIN, MENIERES-DISEASE, NITRIC-OXIDE, HAIR-CELLS, RATS, PREVENTION, ANTIOXIDANT, MODEL, INFLAMMATION
Bezmialem Vakıf University Affiliated: Yes

Abstract

Objectives: The purpose of this study is to evaluate the possible protective role of naringenin in gentamicin-induced ototoxicity through an audiological, biochemical and histopathological evaluation.