Cardioactive Diterpenes from the roots of Salvia eriophora


ULUBELEN A., BIRMAN H., OKSUZ S., Topcu G., KOLAK U., BARLA A., ...More

PLANTA MEDICA, vol.68, no.9, pp.818-821, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 9
  • Publication Date: 2002
  • Doi Number: 10.1055/s-2002-34408
  • Journal Name: PLANTA MEDICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.818-821
  • Keywords: Salvia eriophora, Lamiaceae, abietane and rearranged abietane diterpenes, vasodepressor effect, QUINONES
  • Bezmialem Vakıf University Affiliated: No

Abstract

From the roots of Salvia eriophora (Lamiaceae), a new compound, 4,14-dhydroxysaprorthoquinone, was isolated in addition to ten known diterpenoids. The structure of the new compound was established by spectroscopic analysis. The crude extract of the plant and the isolated diterpenoids were tested for their cardiovascular activities using Wistar Albino rats. Activity was demonstrated in the crude extract and in 4,14-dihydroxysaprorthoquinone, aethiopinone, ferruginol, 4,12-dihydroxysapriparaquinone, and 6,7-dehydroroyleanone.