Cardioactive Diterpenes from the roots of Salvia eriophora


ULUBELEN A., BIRMAN H., OKSUZ S., Topcu G. , KOLAK U., BARLA A., et al.

PLANTA MEDICA, cilt.68, ss.818-821, 2002 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 68 Konu: 9
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1055/s-2002-34408
  • Dergi Adı: PLANTA MEDICA
  • Sayfa Sayısı: ss.818-821

Özet

From the roots of Salvia eriophora (Lamiaceae), a new compound, 4,14-dhydroxysaprorthoquinone, was isolated in addition to ten known diterpenoids. The structure of the new compound was established by spectroscopic analysis. The crude extract of the plant and the isolated diterpenoids were tested for their cardiovascular activities using Wistar Albino rats. Activity was demonstrated in the crude extract and in 4,14-dihydroxysaprorthoquinone, aethiopinone, ferruginol, 4,12-dihydroxysapriparaquinone, and 6,7-dehydroroyleanone.