Curcumin prevents oxidative renal damage induced by acetaminophen in rats.

Cekmen, M.; ILBEY, YUSUF; OZBEK, E.; SIMSEK, A.; SOMAY, A.; Ersoz, CEVPER

doi:10.1016/j.fct.2009.03.034

Curcumin prevents oxidative renal damage induced by acetaminophen in rats.

Cekmen M., ILBEY Y. Ö., OZBEK E., SIMSEK A., SOMAY A., Ersoz C.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, cilt.47, sa.7, ss.1480-4, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 47 Sayı: 7
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.fct.2009.03.034
Dergi Adı: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1480-4
Anahtar Kelimeler: Curcumin, Nephrotoxicity, Acetaminophen, PARACETAMOL OVERDOSAGE, INDUCED NEPHROTOXICITY, ANTIOXIDANT ACTIVITY, LIPID-PEROXIDATION, HEPATIC NECROSIS, COVALENT BINDING, DIETARY CURCUMIN, TOXICITY, LIVER, MICE
Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Acetaminophen (APAP) can cause life-threatening renal damages and there is no specific treatment for APAP-induced renal damage. The aim of this study was to investigate the protective effects of curcumin (CMN) on APAP-induced nephrotoxicity.