Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised

Janssen, HLA; van Zonneveld, M; Senturk, HAKAN; Zeuzem, S; Akarca, US; Cakaloglu, Y; Simon, C; So, TMJ; Gerken, G; de Man, RA; Niesters, HGM; Zondervan, P; Hansen, B; Schalm, SW

doi:10.1016/s0140-6736(05)17701-0

Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised

Janssen H., van Zonneveld M., Senturk H. , Zeuzem S., Akarca U., Cakaloglu Y., ...More

LANCET, vol.365, no.9454, pp.123-129, 2005 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 365 Issue: 9454
Publication Date: 2005
Doi Number: 10.1016/s0140-6736(05)17701-0
Title of Journal : LANCET
Page Numbers: pp.123-129

Abstract

Background Treatment of HBeAg-positive patients with chronic hepatitis B is not effective in most. A combination of immunomodulatory pegylated interferon alfa-2b and antiviral lamivudine might improve the rate of sustained response.