Necrobiosis lipoidica is a granulomatous skin disease whose etiology and pathogenesis are not fully explained. The association of necrobiosis lipoidica with diabetes mellitus is frequently discussed and it is thought that microangiopathy plays an important role. Although there are many treatment options, there is no standard treatment model. In this study; a 43-year-old female patient with common skin lesions and punch biopsy and necrobiosis lipoidica diagnosis was presented. The patient was found to have concomitant diabetes mellitus with necrobiosis lipoidica. After treatment, diabetes mellitus clinic resolves but the necrobiosis lipoidica does not fully recover; Autoimmune hepatitis was detected and immunosuppressive treatment was given and the patient's treatment was provided. In this case report, etiology and treatment of necrobiosis lipoidica have been discussed based on this case.