Assessment of IL-31 levels and disease severity in children with atopic dermatitis

Ozceker D., Bulut M., Ozbay A. C. , Dilek F., Koser M., Tamay Z., ...Daha Fazla

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, cilt.46, sa.4, ss.322-325, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.aller.2017.10.005
  • Sayfa Sayıları: ss.322-325


Introduction and objectives: Atopic dermatitis is a chronic, relapsing, highly pruritic, inflam- matory skin disease characterized by typical localization with increasing prevalence of 10-20% in children. Pruritus is one of the major diagnostic criteria of atopic dermatitis and also the main complaint altering quality-of-life of affected patients, inducing and aggravating inflammation. Although pruritus is the absolute symptom of AD, the etiology has not been fully explained yet and current antihistamine therapies are ineffective.