Assessment of IL-31 levels and disease severity in children with atopic dermatitis


Ozceker D., Bulut M., Ozbay A. C. , Dilek F., Koser M., Tamay Z., ...More

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.46, no.4, pp.322-325, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1016/j.aller.2017.10.005
  • Title of Journal : ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Page Numbers: pp.322-325

Abstract

Introduction and objectives: Atopic dermatitis is a chronic, relapsing, highly pruritic, inflam- matory skin disease characterized by typical localization with increasing prevalence of 10-20% in children. Pruritus is one of the major diagnostic criteria of atopic dermatitis and also the main complaint altering quality-of-life of affected patients, inducing and aggravating inflammation. Although pruritus is the absolute symptom of AD, the etiology has not been fully explained yet and current antihistamine therapies are ineffective.