The effect of surgical denervation on prevention of excessive dermal scarring: A study on rabbit ear hypertrophic scar model

YAGMUR C., Guneren E., Kefeli M., OGAWA R.

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, vol.64, no.10, pp.1359-1365, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 10
  • Publication Date: 2011
  • Doi Number: 10.1016/j.bjps.2011.04.028
  • Journal Name: JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1359-1365
  • Keywords: Hypertrophic scar, Keloid, Nerve, Denervation, Sensory denervation, Mechanosensitive nociceptor, Neuropeptide, Neurogenic inflammation, Substance P, Free nerve ending, Axon reflex, GENE-RELATED PEPTIDE, SENSORY DENERVATION, WOUND CONTRACTION, SUBSTANCE-P, RAT SKIN, INHIBITION, QUANTIFICATION, PROLIFERATION, INFLAMMATION, INNERVATION
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Background: Previous reports have suggested that the extent of wound contraction, epithelisation and total healing time were influenced by denervation of tissues. In this article, we studied for the first time the effect of sensory denervation on prevention of excessive dermal scarring. Materials and