Mesenchymal stem cell therapy for the streptozotocin-induced neurodegeneration in rats

Isik A. T., Celik T., URAL A. U., Tosun M., ULUSOY G., Elibol B.

NEUROLOGICAL RESEARCH, vol.38, no.4, pp.364-372, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.1080/01616412.2016.1139292
  • Journal Name: NEUROLOGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.364-372
  • Keywords: Neurodegeneration, Mesenchymal stem cell, Alzheimer's disease, Experimental model, TRAUMATIC BRAIN-INJURY, ALZHEIMERS-DISEASE, MARROW, MODEL, TRANSPLANTATION, NEUROGENESIS, MICE, DIFFERENTIATION, MICROGLIA, PATHOLOGY
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Background and Aim: Bone marrow-derived mesenchymal stem cells (BM-MSCs) are one of the sources of adult stem cells being explored for potential use in repairing neurodegenerative disorders. In this study, it was aimed to investigate the useful effects of BM-MSCs therapy on the streptozotocin-induced neurodegeneration in rats.