Phytochemical Investigation of Leontice leontopetalum L. subsp ewersmannii with Antioxidant and Anticholinesterase Activities


Kolak U., Hacibekiroglu I. , Boga M., Özgökçe F., Ünal M., CHOUDHARY M. I. , ...More

RECORDS OF NATURAL PRODUCTS, vol.5, no.4, pp.309-313, 2011 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 4
  • Publication Date: 2011
  • Title of Journal : RECORDS OF NATURAL PRODUCTS
  • Page Numbers: pp.309-313
  • Keywords: Leontice leontopetalum L. subsp ewersmannii, Berberidaceae, lupanine, anticholinesterase, ALKALOIDS

Abstract

Two known quinolizidine alkaloids, lupanine and leontiformidine, were isolated from the tubers of L. leontopetalum subsp. ewersmannii. Lupanine having the highest inhibition of lipid peroxidation at 100 mu g/mL among the tested samples indicated almost the same ABTS cation radical scavenging activity with BHT, alpha-tocopherol and (+)-catechin at the same concentration. Lupanine and the alkaloidal extract showed almost the same butyrylcholinesterase inhibitory activity with galantamine at 200 mu g/mL.