Phytochemical Investigation of Leontice leontopetalum L. subsp ewersmannii with Antioxidant and Anticholinesterase Activities


Kolak U., Hacibekiroglu I. , Boga M., Özgökçe F., Ünal M., CHOUDHARY M. I. , et al.

RECORDS OF NATURAL PRODUCTS, cilt.5, ss.309-313, 2011 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 5 Konu: 4
  • Basım Tarihi: 2011
  • Dergi Adı: RECORDS OF NATURAL PRODUCTS
  • Sayfa Sayısı: ss.309-313

Özet

Two known quinolizidine alkaloids, lupanine and leontiformidine, were isolated from the tubers of L. leontopetalum subsp. ewersmannii. Lupanine having the highest inhibition of lipid peroxidation at 100 mu g/mL among the tested samples indicated almost the same ABTS cation radical scavenging activity with BHT, alpha-tocopherol and (+)-catechin at the same concentration. Lupanine and the alkaloidal extract showed almost the same butyrylcholinesterase inhibitory activity with galantamine at 200 mu g/mL.