Growth Arrest-Specific 6 and Cardiometabolic Risk Factors in Patients with Psoriasis


SÜNBÜL M., Cagman Z. , Gerin F., ÖZGEN Z., Durmus E., Seckin D., ...More

CARDIOVASCULAR THERAPEUTICS, vol.33, no.2, pp.56-61, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1111/1755-5922.12112
  • Title of Journal : CARDIOVASCULAR THERAPEUTICS
  • Page Numbers: pp.56-61

Abstract

ObjectivesAn increased risk for cardiovascular disease with psoriasis has been reported. Growth Arrest-Specific 6 (GAS6) amplifies pro-inflammatory endothelial cell activation via TAM receptors. However, it also inhibits inflammation by multiple mechanisms including phagocytosis. The objective of this study was to investigate whether plasma GAS6 levels are associated with conventional cardiometabolic (CM) risk factors in patients with psoriasis.