Neurologia i neurochirurgia polska, vol.54, pp.576-584, 2020 (SCI-Expanded)
Article / Article
Neurologia i neurochirurgia polska
Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
aneurysm, thymoquinone, oxidative stress, subarachnoid haemorrhage, cerebral vasospasm, delayed cerebral injury, ISCHEMIA-REPERFUSION INJURY, NIGELLA-SATIVA, BRAIN, MODEL, NEURODEGENERATION, PROLIFERATION, NEURONS, SEED
Bezmialem Vakıf University Affiliated:
Aim of the study. Among subarachnoid haemorrhage (SAH) patients, delayed cerebral injury (DCI) and infarction are the most important causes of death and major disability. Cerebral vasospasm (cVS) and DCI remain the major cause of death and disability. Thymoquinone (TQ) is the substance most responsible for the biological activity of nigella sativa (NS) and is useful in the treatment of ischaemic and neurodegenerative diseases, oxidative stress, inflammatory events, cardiovascular and neurological diseases. We conducted an experimental study aimed to investigate the preventive and corrective effects of TQ.