THE EFFECTS OF GLYBURIDE AND INSULIN ON THE DECREASED BETA-ADRENERGIC RESPONSIVENESS OF THE GASTROINTESTINAL-TRACT IN RATS WITH NON-INSULIN-DEPENDENT DIABETES


OZTURK Y., YILDIZOGLUARI N., OZÜARI A., ALTAN V. M.

GENERAL PHARMACOLOGY, vol.25, no.7, pp.1511-1517, 1994 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 7
  • Publication Date: 1994
  • Doi Number: 10.1016/0306-3623(94)90182-1
  • Title of Journal : GENERAL PHARMACOLOGY
  • Page Numbers: pp.1511-1517

Abstract

1. Decreased beta-adrenergic responses have been reported in gastro-intestinal tract of rats with diabetes mellitus. Effects of glyburide and insulin on the decreased beta-adrenergic responsiveness of the gastro-intestinal tract due to non-insulin-dependent diabetes were investigated using duodenum, jejunum and ileum from rats which were injected with alloxan in their neonatal periods.