Are There Any Systemic Effects of the Intratympanic Administration of Dexamethasone?

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Senturk E., Tugrul S., Yildirim Y. S., DOĞAN R., EREN S. B., ÖZTURAN O.

BEZMIALEM SCIENCE, cilt.6, sa.3, ss.186-190, 2018 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.14235/bs.2018.1943
  • Dergi Adı: BEZMIALEM SCIENCE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.186-190
  • Anahtar Kelimeler: Inner ear diseases, intratympanic steroids, systemic effects, SENSORINEURAL HEARING-LOSS, INNER-EAR, CORTICOSTEROID PHARMACOKINETICS, FLUIDS
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Objective: Systemic absorption of steroids is reasonable because of the lipophilic nature of steroids and high vascularity of the middle ear mucosa. To date, however, of the clinical trials designed to investigate this subject, to the best of our knowledge, none has been based on objective methods. This study aims to demonstrate whether the intratympanic administration of dexamethasone has any systemic effects.