Evaluation of mean platelet volume in localized scleroderma.

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Bahali A. G. , Su Ö. S. , Emiroglu N. , Cengiz F. P. , Kaya M. O. , Onsun N.

Anais brasileiros de dermatologia, vol.92, no.5, pp.635-637, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 92 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1590/abd1806-4841.20176045
  • Title of Journal : Anais brasileiros de dermatologia
  • Page Numbers: pp.635-637
  • Keywords: Blood platelets, Scleroderma, localized, Transforming growth factor beta, SYSTEMIC-SCLEROSIS, PATHOGENESIS, MORPHEA, INFLAMMATION, INVOLVEMENT, UPDATE

Abstract

BACKGROUND: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation. Following activation, platelets rapidly release numerous mediators and cytokines, which contribute to inflammation.