Evaluation of mean platelet volume in localized scleroderma.

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Bahali A. G., Su Ö. S., Emiroglu N., Cengiz F. P., Kaya M. O., Onsun N.

Anais brasileiros de dermatologia, vol.92, no.5, pp.635-637, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 92 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1590/abd1806-4841.20176045
  • Journal Name: Anais brasileiros de dermatologia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.635-637
  • Keywords: Blood platelets, Scleroderma, localized, Transforming growth factor beta, SYSTEMIC-SCLEROSIS, PATHOGENESIS, MORPHEA, INFLAMMATION, INVOLVEMENT, UPDATE
  • Open Archive Collection: AVESIS Open Access Collection
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

BACKGROUND: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation. Following activation, platelets rapidly release numerous mediators and cytokines, which contribute to inflammation.