Anais brasileiros de dermatologia, vol.92, no.5, pp.635-637, 2017 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Anais brasileiros de dermatologia
Blood platelets, Scleroderma, localized, Transforming growth factor beta, SYSTEMIC-SCLEROSIS, PATHOGENESIS, MORPHEA, INFLAMMATION, INVOLVEMENT, UPDATE
BACKGROUND: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation. Following activation, platelets rapidly release numerous mediators and cytokines, which contribute to inflammation.