Amantadine monotherapy of chronic hepatitis C patients infected with genotype 1b

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Senturk H., Mert A., Akdogan M., TABAK Ö. F., Basaran G., Turkoglu S., ...More

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, vol.32, no.5, pp.575-576, 2000 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 32 Issue: 5
• Publication Date: 2000
• Doi Number: 10.1080/003655400458965
• Journal Name: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.575-576
• Bezmialem Vakıf University Affiliated: Yes

Abstract

We aimed to test the efficacy of amantadine in chronic hepatitis C (CHC) patients infected with genotype Ib. Twenty patients completed treatment with amantadine HCl, 100 mg b.i.d., for 6 months. Non-sustained biochemical improvement was observed without loss of HCV-RNA, We conclude that amantadine monotherapy is not effective in CHC.