Comparison of the biochemical and radiological criteria for lumbar disc degeneration

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Seyithanoglu M. H., Kitis S., Ozer O. F., Kocyigit A., DÜNDAR T., Papaker M. G., ...More

NEUROLOGIA I NEUROCHIRURGIA POLSKA, vol.52, no.5, pp.570-574, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1016/j.pjnns.2018.01.008
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.570-574
  • Keywords: Lumbar disc herniation, Radiological degeneration, Grading system, Keratan sulfate, Chondroitin sulfate, RESONANCE, VARIABILITY
  • Bezmialem Vakıf University Affiliated: Yes


Background: The relationship between radiological degeneration criteria on lumbar magnetic resonance imaging (MRI) and both the keratan sulfate (KS) and chondroitin sulfate (ChS) levels was examined in disc material taken from patients undergoing lumbar disc herniation (LDH) surgery. To examine whether the biochemical and radiological degeneration criteria testing the reliability of radiological degeneration findings agreed and to evaluate the contribution of the KS/ChS ratio to disc form (protruding or extruding).