Clinical and polysomnographic features of a large Turkish pedigree with restless leg syndrome and periodic limb movements

Babacan-Yildiz G., Gursoy E., Kolukisa M., Karakose F., Akkoyunlu E. M., CELEBI A., ...More

SLEEP AND BREATHING, vol.17, no.2, pp.741-746, 2013 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1007/s11325-012-0756-5
  • Journal Name: SLEEP AND BREATHING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.741-746
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Restless leg syndrome (RLS) and periodic limb movements (PLMS) are common neurological diseases often associated with insomnia. A familial aggregation in RLS has been identified since it was first described; however, inheritance patterns of RLS/PLMS are poorly understood and their exact pathophysiology is not well-known. We have identified a Turkish pedigree with RLS/PLMS, which is a rare condition, in five generations of a family, including nine affected family members.