Which Rivastigmine Formula is Better for Heart in Elderly Patients With Alzheimer's Disease: Oral or Patch?


Isik A. T. , Soysal P. , YAY A.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS, vol.29, no.8, pp.735-738, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 8
  • Publication Date: 2014
  • Doi Number: 10.1177/1533317514536598
  • Title of Journal : AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS
  • Page Numbers: pp.735-738
  • Keywords: rivastigmine patch, oral rivastigmine, Alzheimer's disease, arrhythmia, hypotension, elderly, TRANSDERMAL PATCH, DOUBLE-BLIND, QT INTERVAL, POPULATION, 6-MONTH

Abstract

Objective: Rivastigmine is commonly used for the treatment of Alzheimer's disease (AD). All cholinesterase inhibitors, including rivastigmine, may cause cardiac side effects. The aim of this study is to compare the electrocardiographic (ECG) and hypotensive effects of formulations of rivastigmine.