Simvastatin improves spinal fusion in rats


Bostan B., Gunes T., AŞCI M., Sen C., Kelestemur M. H. , Erdem M., ...More

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.45, no.4, pp.270-275, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.3944/aott.2011.2526
  • Title of Journal : ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Page Numbers: pp.270-275

Abstract

Objective: Statins stimulate bone formation by inducing the expression of bone morphogenetic proteins (BMP-2). The aim of our study was to investigate the effects of orally administered simvastatin on spinal fusion in rats.