Simvastatin improves spinal fusion in rats

Bostan B., Gunes T., AŞCI M., Sen C., Kelestemur M. H. , Erdem M., ...Daha Fazla

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.45, sa.4, ss.270-275, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 45 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3944/aott.2011.2526
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Sayfa Sayıları: ss.270-275

Özet

Objective: Statins stimulate bone formation by inducing the expression of bone morphogenetic proteins (BMP-2). The aim of our study was to investigate the effects of orally administered simvastatin on spinal fusion in rats.