Simvastatin improves spinal fusion in rats

Bostan, Bora; Gunes, Taner; AŞCI, MURAT; Sen, Cengiz; Kelestemur, Mehmet; Erdem, Mehmet; KÖSEOĞLU, REŞİT; Erkorkmaz, Unal

doi:10.3944/aott.2011.2526

Simvastatin improves spinal fusion in rats

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Bostan B., Gunes T., AŞCI M., Sen C., Kelestemur M. H. , Erdem M., ...More

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.45, no.4, pp.270-275, 2011 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 45 Issue: 4
Publication Date: 2011
Doi Number: 10.3944/aott.2011.2526
Title of Journal : ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
Page Numbers: pp.270-275

Abstract

Objective: Statins stimulate bone formation by inducing the expression of bone morphogenetic proteins (BMP-2). The aim of our study was to investigate the effects of orally administered simvastatin on spinal fusion in rats.