OBJECTIVE: We aimed to investigate the relationship between gastroscopic fi ndings and Helicobacter pylori (H. pylori) in uremic patients; and to compare them with the normal population. MATERIAL and METHODS: Sixty two patients who had dyspeptic symptoms and who had a gastroscopic examination were included. These patients were grouped as hemodialysis group (n=29); peritoneal dialysis group (n=12), predialysis group (n=29) and the control group (n=29). RESULTS: On pathological examinations of biopsies obtained for all participants of the study; 20 patients had gastritis, two had duodenitis, 14 had H. pylori positivity and one had malignancy in the hemodialysis group. Of the 12 peritoneal dialysis patients; 11 had gastritis, three had duodenitis and seven had H. pylori positivity. Twenty eight of the 29 predialysis patients had gastritis, two had duodenitis, 22 had H. pylori positivity. Of the 29 control subjects; 27 had gastritis, seven had duodenitis and 19 had H. pylori positivity. There was no difference between groups regarding gastroscopic and histopathological fi ndings. The use of proton pump inhibitors did not affect these fi ndings. CONCLUSION: In spite of the differences in gastric mucosal physiology in uremia; the rate of H. pylori infection and gastroscopic fi ndings are not different in uremic and nonuremic population.