Determination of Antioxidant, Anticholinesterase, Tyrosinase Inhibitory Activities and Fatty Acid Profiles of 10 Anatolian Klasea Cass. Species

Tel G., Dogan B., EROL E., Ozturk M., Nadeem S., Ullah Z., ...More

RECORDS OF NATURAL PRODUCTS, vol.10, no.1, pp.122-127, 2016 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 1
  • Publication Date: 2016
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.122-127
  • Keywords: Klasea species, tyrosinase inhibitory activity, anticholinesterase activity, antioxidant activity, phenolic and flavonoid contents, fatty acids, DISEASE
  • Bezmialem Vakıf University Affiliated: Yes


In search of new natural fatty acid sources, extract of 10 different Turkish Klasea species were studies. Fatty acids of Klasea species were studied by GC and GC-MSD. Oleic acid (4.8-45.8%), palmitic acid (15.6-51.8%), linoleic acid (0.3-45.5%), palmitoleic acid (0.8-28.4%) and linolenic acid (15.6-34.6%) were the main fatty acids elucidated. All extracts were also subjected to acetylcholinesterase, butyrylcholinesterase, tyrosinase, beta-carotene-linoleic acid, DPPH center dot scavenging, CUPRAC and ferrous ion-chelating ability activities. Total flavonoid and phenolic contents were determined as quercetin and pyrocatechol equivalents. All extracts showed significant antioxidant activity in all tests, except hexane extracts of K. serratuloides and K. cerinthifolia that showed weak inhibition against BChE and AChE. The hexane extract of K. coriaceae and methanol extract of K. serratuloides exhibited notable tyrosinase inhibitory activity.