The relation of urinary bisphenol A with kisspeptin in girls diagnosed with central precocious puberty and premature thelarche.

Ozgen I. T. , Torun E. , Bayraktar-Tanyeri B. , Durmaz E., Kilic E., Cesur Y.

Journal of pediatric endocrinology & metabolism : JPEM, vol.29, no.3, pp.337-41, 2016 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1515/jpem-2015-0235
  • Title of Journal : Journal of pediatric endocrinology & metabolism : JPEM
  • Page Numbers: pp.337-41


Background: Bisphenol A (BPA) is known as an endocrine disruptor and it is supposed to have a role on the development of central precocious puberty (CPP). Kisspeptin, a hypothalamic peptide, is a neuromodulator of gonadotropin releasing hormone and it has an important role on regulation of the onset of puberty. The BPA levels in girls with CPP and premature thelarche (PT) and its relation with kisspeptin levels were investigated.