Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors.

Akdemir A., Rucktooa P., Jongejan A., Van Elk R., Bertrand S., Sixma T., ...More

Bioorganic & medicinal chemistry, vol.19, pp.6107-19, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19
  • Publication Date: 2011
  • Doi Number: 10.1016/j.bmc.2011.08.028
  • Journal Name: Bioorganic & medicinal chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.6107-19
  • Keywords: Nicotinic acetylcholine receptors (nAChR), Acetylcholine binding protein (AChBP), Electrophysiology, In silico screening, Virtual screening, Docking, Crystallization, Ligand-gated ion channels (LGICs), Cys-loop receptors, GATED ION-CHANNEL, X-RAY-STRUCTURE, CRYSTAL-STRUCTURE, MOLECULAR RECOGNITION, EXTRACELLULAR DOMAIN, THROMBIN INHIBITORS, AGONIST-BINDING, HOMOLOG ACHBP, DOCKING, ANTAGONISTS
  • Bezmialem Vakıf University Affiliated: Yes