Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+-dependent Cl- conductance


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Kose H. , Boese S., Glanville M., Gray M., Brown C., Simmons N.

BRITISH JOURNAL OF PHARMACOLOGY, vol.131, no.8, pp.1689-1699, 2000 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 131 Issue: 8
  • Publication Date: 2000
  • Doi Number: 10.1038/sj.bjp.0703749
  • Title of Journal : BRITISH JOURNAL OF PHARMACOLOGY
  • Page Numbers: pp.1689-1699
  • Keywords: inner medullary collecting duct, IMCD, bradykinin, renal epithelial salt transport, Cl- secretion, Ca2+-dependent Cl- conductance, CFTR, SENSITIVE CHLORIDE CHANNEL, HUMAN TISSUE KALLIKREIN, FUNCTIONAL-ANALYSIS, MAMMARY-GLAND, CELL-LINE, SECRETION, CLONING, PROSTAGLANDIN, GENERATION, RECEPTORS

Abstract

1 The mechanism by which bradykinin regulates renal epithelial salt transport has been investigated using a mouse inner medullary renal collecting duct cell-line mIMCD-K2.