Serum lipid and lipoprotein changes induced by preparations containing low-dose ethinylestradiol plus levonorgestrel

Kiran G., Kiran H., Ekerbicer H. C.

Australian and New Zealand Journal of Obstetrics and Gynaecology, cilt.43, sa.2, ss.145-147, 2003 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 2
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1046/j.0004-8666.2003.00033.x
  • Dergi Adı: Australian and New Zealand Journal of Obstetrics and Gynaecology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.145-147
  • Anahtar Kelimeler: Ethinylestradiol, Levonorgestrel, Lipid changes, Low-dose monophasic combination oral contraceptive
  • Bezmiâlem Vakıf Üniversitesi Adresli: Hayır

Özet

The purpose of the present study was to evaluate the effects on lipid metabolism of a new low-dose monophasic combination oral contraceptive with 100 μg levonorgestrel and 20 μg ethinylestradiol. Sixty healthy women aged 18-45 years were administered the medication during three cycles. The study participants were screened for lipid changes. The differences in cholesterol and triglyceride levels were not statistically significant, but high-density lipoprotein levels were significantly lower and low-density lipoprotein levels were significantly higher than the baseline. Women at risk of cardiovascular disease should be carefully monitored even when using low-dose preparations.