Increased oxidant status in children with breath-holding spells

Calik M., Abuhandan M., Aycicek A., Taskin A., Selek S. , Iscan A.

CHILDS NERVOUS SYSTEM, cilt.29, sa.6, ss.1015-1019, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00381-012-2001-8
  • Sayfa Sayıları: ss.1015-1019


Breath-holding spells (BHS) are the most common form of non-epileptic paroxysmal events in infancy. The pathophysiology of BHS is not fully understood. Iron-deficiency anemia (IDA) may be a factor contributing to breath-holding spells. Although numerous reports have shown that elevated oxidative stress is implicated in the pathophysiology of neurodegenerative diseases and neurological conditions, such as epileptic seizures, brain damage, and neurotrauma, there are no data regarding the role of oxidative stress in the development of BHS. This study aimed to investigate oxidative stress in children with BHS.