Pyoderma gangrenosum (PG) is a reactive neutrophilic dermatosis, accompanying inflammatory bowel diseases such as ulcerative colitis, Crohn's disease, lymphoproliferative disorders and rheumatic diseases. It is generally characterized by painful, ulcerative lesions with violaceous borders. Lesions are mostly located on face, upper extremities and dorsum of the hand. The aetiology of disease is unknown. The subtypes of disease are ulcerative, bullous, pustular and vegetative types of PG. The differential diagnosis of PG includes arterial and venous ulcers, bacterial and mycotic infections, vasculitides, cancer, syphilis and Sweet syndrome. Although there is no effective treatment of the disease, immunosupressive agents such as topical and systemic corticosteroids, cyclosporine, methotrexate are used in the treatment. Herein, a case of PG located on an atypical site, on scalp was reported.