The effect of local simvastatin application on critical size defects in the diabetic rats

EZIRGANLI S., KAZANCIOGLU H. O., MIHMANLI A., AYDIN M. S., Sharifov R., Alkan A.

CLINICAL ORAL IMPLANTS RESEARCH, vol.25, no.8, pp.969-976, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 8
  • Publication Date: 2014
  • Doi Number: 10.1111/clr.12177
  • Journal Name: CLINICAL ORAL IMPLANTS RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.969-976
  • Keywords: bone healing, computerized tomography, critical size defect, diabetic rat, histomorphometry, simvastatin, BONE MORPHOGENETIC PROTEIN-2, ENDOTHELIAL GROWTH-FACTOR, PLATELET-RICH PLASMA, ANTIINFLAMMATORY ROLE, MEMBRANE TECHNIQUE, CALVARIAL DEFECTS, SKULL DEFECTS, REPAIR, FRACTURE, MODEL
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Objectives: To evaluate bone-healing effects of local simvastatin application to critical size defects (CSDs) in the experimental diabetes mellitus (DM) rat model.