Sertoli leydig cell tumor of the ovary in a woman with cushing syndrome: A case report

Ofli T., KIRAN G., Kunt A.

Gynecologic Oncology Reports, cilt.49, 2023 (ESCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.gore.2023.101277
  • Dergi Adı: Gynecologic Oncology Reports
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Anahtar Kelimeler: Androgenism, Cushing's syndrome, Paraplegia, Sertoli leydig cell tumor
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Sertoli-Leydig cell tumor (SLCT) is a rare tumor of the ovary.Cushing's syndrome (CS), on the other hand, is a clinical picture formed by the long-term high levels of glucocorticoids in the blood for any reason and the resulting symptoms. Exceptionally in some of cases, a tumor far from the adrenal region synthesizes adrenocortical hormones. Among such ectopic neoplasms, CS Tumors of the ovary that secrete cortisol as a cause of the disease is an exceptional case. In other words, in this case, we argue that the tumor in the ovary causes Cushing's syndrome by secreting cortisol and ACTH-like peptides. There are 5 cases reported in the literature. In this case report we present a case in which SCLT of the ovary was detected by histopathological examination in a patient who underwent laparoscopic surgery due to Cushing's syndrome and bilateral adnexal mass.