Clinical and Radiological Features in CADASIL and NOTCH3-Negative Patients: A Multicenter Study from Turkey


Ince B., Benbir G., Siva A., Saip S., Utku U., Celik Y., et al.

EUROPEAN NEUROLOGY, cilt.72, ss.125-131, 2014 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 72
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1159/000360530
  • Dergi Adı: EUROPEAN NEUROLOGY
  • Sayfa Sayısı: ss.125-131

Özet

Background: The diversity of clinical presentation and neuroimaging findings of CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) from different regions of the world has not yet been studied in depth. Here we investigated the variability of clinical, radiological and genetic data of 48 patients analyzed for NOTCH3 mutation in Turkey.