Clinical and Radiological Features in CADASIL and NOTCH3-Negative Patients: A Multicenter Study from Turkey

Ince B., Benbir G., Siva A., Saip S., Utku U., Celik Y., ...More

EUROPEAN NEUROLOGY, vol.72, pp.125-131, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72
  • Publication Date: 2014
  • Doi Number: 10.1159/000360530
  • Journal Name: EUROPEAN NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.125-131
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Background: The diversity of clinical presentation and neuroimaging findings of CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) from different regions of the world has not yet been studied in depth. Here we investigated the variability of clinical, radiological and genetic data of 48 patients analyzed for NOTCH3 mutation in Turkey.