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Bektay M. Y., Güler E. M., Gökçe M., Kızıltaş M. V.
Turkish journal of pharmaceutical sciences, vol.18, no.6, pp.781-789, 2021 (ESCI)
Article / Article
Turkish journal of pharmaceutical sciences
Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, International Pharmaceutical Abstracts, TR DİZİN (ULAKBİM)
Olive leaf, hepatocellular carcinoma, oleuropein, oxidative stress, genotoxicity, apoptosis, ANTIOXIDANT ACTIVITY, OLEUROPEIN, POLYPHENOLS, PROLIFERATION, DAMAGE, TREE
Bezmialem Vakıf University Affiliated:
Objectives: Hepatocellular carcinoma (HCC) is the seventh most common cancer and the third leading cause of tumor-related deaths worldwide. Mechanisms underlying tumor onset, progression, and metastasis in the case of HCC have not been adequately studied. In this study, we aimed to investigate the genotoxic, cytotoxic, apoptotic and oxidant effects of olive leaf extract (OLE) on HCC cells.