The effect of mesenchymal stem cells and sildenafil on flap viability in perforator-based flaps for ischemia/reperfusion injury: An experimental study

Kelahmetoglu O. , Demir R., Okten G., Demir A., Alpaslan Pinarli F., Diraman E.

MICROSURGERY, vol.36, no.5, pp.402-409, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1002/micr.22396
  • Title of Journal : MICROSURGERY
  • Page Numbers: pp.402-409


PurposeIn this study, we evaluated the individual and combined effects of mesenchymal stem cells (MSCs) and sildenafil citrate (SC) on the viability of pedicled perforator flaps in which ischemia/reperfusion injury developed after induction of primary ischemia.