Leucine-rich alpha-2 glycoprotein (LRG): A novel acute phase protein expressed in stage 3 grade C periodontitis before and after periodontal therapy

Keles Yucel Z. P., Balli U.

JOURNAL OF PERIODONTOLOGY, vol.92, no.1, pp.104-112, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 92 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1002/jper.20-0358
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, DIALNET
  • Page Numbers: pp.104-112
  • Bezmialem Vakıf University Affiliated: No

Abstract

Background Leucine-rich alpha-2 glycoprotein (LRG) is a novel acute phase protein involved in inflammation-associated diseases and that considered to be induced by multiple proinflammatory cytokines. This study aimed to investigate gingival crevicular fluid (GCF) and serum levels of LRG, interleukin (IL)-6 and tumor necrosis factor (TNF)-alpha in patients with stage 3 periodontitis before and after non-surgical periodontal treatment.