Integrase inhibitor-based antiretroviral treatments decrease oxidative stress caused by HIV infection.

Akkoyunlu Y., Kocyigit A., Okay G., Guler E. M., Aslan T.

European review for medical and pharmacological sciences, cilt.24, ss.12389-12394, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24
  • Basım Tarihi: 2020
  • Doi Numarası: 10.26355/eurrev_202012_24033
  • Dergi Adı: European review for medical and pharmacological sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.12389-12394
  • Anahtar Kelimeler: Oxidative stress, HIV infection, Integrase inhibitor-based antiretroviral treatment, SERUM MALONDIALDEHYDE, REDOX, INDIVIDUALS, LYMPHOCYTES, CHILDREN, PROFILE, PLASMA
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Several chronic illnesses, including HIV infection are associated with oxidative stress. In addition to HIV itself, some antiretrovirals also increase oxidative stress while decreasing viral replication. To investigate the alterations in oxidative stress parameters and thiol-disulphide homeostasis in people living with HIV who were receiving integrase inhibitor-based antiretroviral therapy.