Akademik Veri Yönetim Sistemi
Asia Pacific journal of clinical nutrition, cilt.34, sa.4, ss.589-595, 2025 (SCI-Expanded, Scopus)
Background
Obesity and obesity-related diseases is increasing worldwide. The widely accepted
approach in the dietary treatment of obesity is the calorie-restricted six meal diet; however,
alternative approaches are needed. This study aimed to compare time-restricted eating (TRE),
a method that can be easily conveyed and applied in over-coming obesity, to six meals diet.
Methods
A total of 174 participants aged 18-65, BMI>25 kg/m 2 were included, with 88
participants in the time-restricted eating group and 86 participants in the six-meal group. Diet
lists with similar calorie, macro counts suitable for their respective groups were prepared.
Anthropometric measurements, blood pressure, blood tests were analyzed before the study
and at the end of the 8-week.
Results
More weight loss [MD: 1.17 kg, (95% CI: 0.23-2.06), Cohen’s d=0.42], higher
decrease in BMI [MD: 0.41 kg/m 2 (95% CI: -0.77 to -0.06), Cohen’s d=0.39] , decrease in
waist-to-hip ratio [MD: 0.008 (95% CI: -0.016-0.000), Cohen’s d=0.35], decrease in obesity
degree [MD: 2.35 (95% CI: -3.99 to -0.70), Cohen’s d=0.50] were observed in the time-
restricted eating group (p<0.05). In the six meals group, decrease in LDL values was higher
compared to the time-restricted eating group [p<0.05, MD:0.23 mmol/L (95% Cl:0.41-15.79),
Cohen’s d=0.36]. More participants preferred to continue TRE (p<0.001).
Conclusions
TRE resulted in greater weight loss, body fat reduction, and improved metabolic
parameters, proving more effective for weight management. The six-meal diet was superior
for LDL reduction. Both approaches yielded positive outcomes, with TRE emerging as an
alternative weight loss strategy.
Keywords: Obesity, Nutrition Therapy, Time-Restricted Eating, Weight Loss, Intermittent
Fasting