Chemical constituents of essential oil of endemic Rhanterium suaveolens Desf. growing in Algerian Sahara with antibiofilm, antioxidant and anticholinesterase activities

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Chemsa A. E., Erol E., Ozturk M., Zellagui A., Ozgur C., Gherraf N., ...More

NATURAL PRODUCT RESEARCH, vol.30, no.18, pp.2120-2124, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 18
  • Publication Date: 2016
  • Doi Number: 10.1080/14786419.2015.1110705
  • Journal Name: NATURAL PRODUCT RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2120-2124
  • Keywords: Rhanterium suaveolens, essential oil, antibiofilm, anticholinesterase, antioxidant activity, ANTIMICROBIAL ACTIVITIES, RANTHERIUM-SUAVEOLENS, ADPRESSUM
  • Bezmialem Vakıf University Affiliated: No

Abstract

Twenty compounds were detected in the essential oil of Rhanterium suaveolens representing 98.01% of the total oil content. Perillaldehyde (45.79%), caryophyllene oxide (24.82%) and -cadinol (5.61%) were identified as the main constituents. In -carotene-linoleic acid assay, both the oil and the methanol extract exhibited good lipid peroxidation inhibition activity, with IC50 values of 17.97 +/- 5.40 and 11.55 +/- 3.39g/mL, respectively. In DPPH and CUPRAC assays, however, the methanol extract exhibited a good antioxidant activity. The highest antibiofilm activity has been found 50.30% against Staphylococcus epidermidis (MU 30) at 20g/mL for essential oil and 58.34% against Micrococcus luteus (NRRL B-4375) at 25mg/mL concentration for methanol extract. The in vitro anticholinesterase activity of methanol extract showed a moderate acetylcholinesterase inhibitory (IC50=168.76 +/- 0.62g/mL) and good butyrylcholinesterase inhibitory (IC50=54.79 +/- 1.89g/mL) activities. The essential oil was inactive against both enzymes.