Nonalcoholic Wernicke's encephalopathy with prominent astasia and optic neuropathy

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Gokce M., Bulbuloglu E., Tuncel D., Ozdemir G., Kale I.

MEDICAL PRINCIPLES AND PRACTICE, vol.14, no.6, pp.438-440, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1159/000088119
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.438-440
  • Keywords: Wernicke's encephalopathy, thiamine deficiency, gastrointestinal surgery, astasia, optic neuropathy, THIAMINE-DEFICIENCY
  • Bezmialem Vakıf University Affiliated: No


Objective: To present a case with nonalcoholic Wernicke's encephalopathy ( WE) developing astasia and optic neuropathy as major sequelae. Clinical Presentation and Intervention: A 47-year-old woman developed WE following operation for pyloric stenosis. She received total parenteral nutrition before and after operation, but on the second postoperative day she developed visual hallucination and confusion, followed by nystagmus, ophthalmoplegia, apathy, dysarthria and coma. Although the patient has recovered with thiamine treatment, astasia and optic neuropathy persisted as major morbidities. Conclusion: The report shows that astasia and optic neuropathy may be prominent sequelae in some patients with WE. Copyright (C) 2005 S. Karger AG, Basel.