Risk of endocrine pancreatic insufficiency in patients receiving adjuvant chemoradiation for resected gastric cancer

Gemici C., Sargin M., Uygur-Bayramicli O., Mayadagli A., Yaprak G., Dabak R., ...Daha Fazla

RADIOTHERAPY AND ONCOLOGY, cilt.107, sa.2, ss.195-199, 2013 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 107 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.radonc.2013.04.013
  • Dergi Adı: RADIOTHERAPY AND ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.195-199
  • Anahtar Kelimeler: Gastric cancer, Adjuvant radiotherapy, Endocrine pancreatic insufficiency, Diabetes mellitus, BONE-MARROW-TRANSPLANTATION, IMPAIRED GLUCOSE-TOLERANCE, LONG-TERM SURVIVORS, DIABETES-MELLITUS, ABDOMINAL RADIOTHERAPY, CHILDHOOD-CANCER, IRRADIATION, HYPERINSULINEMIA, HOMEOSTASIS, DUODENUM
  • Bezmiâlem Vakıf Üniversitesi Adresli: Hayır

Özet

Background: Adjuvant radiotherapy combined with 5-fluorouracil based chemotherapy has become the new standard after curative resection in high risk gastric cancer. Beside many complications due to surgery, the addition of chemotherapy and radiotherapy as adjuvant treatment may lead to both acute and late toxicities. Pancreatic tissue irradiation during this adjuvant treatment because of incidental and unavoidable inclusion of the organ within the radiation field may affect exocrine and endocrine functions of the organ.