The number of cancer cases has been increasing worldwide.
Early diagnosis and tumor resection remain as the most effective
treatments for gastric cancer. However, early diagnosis is not always
possible as it is frequently not possible to make treatment decisions
without pathologic diagnosis in patients with clinically suspected
cancer. This causes delays in diagnosing cancer. We presented a 58
years old woman with gastric signet ring cell carcinoma that could
not be diagnosed despite using four different methods of stomach
biopsies. We aimed to emphasize that despite the use of advanced
methods, if clinical cancer in non-diagnosed cases is suspected, we
should be more aggressive for early diagnosis.