Primary cutaneous immunocytoma/marginal zone B-cell lymphoma: A case with unusual course


DEMIRKESEN C., TUZUNER N., Su O. , ESCKAZAN A., SOYSAL T., ONSUN N.

AMERICAN JOURNAL OF DERMATOPATHOLOGY, vol.26, no.2, pp.119-122, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 2
  • Publication Date: 2004
  • Doi Number: 10.1097/00000372-200404000-00006
  • Title of Journal : AMERICAN JOURNAL OF DERMATOPATHOLOGY
  • Page Numbers: pp.119-122

Abstract

Although primary cutaneous immunocytoma/marginal zone B-cell lymphoma (PCI/MZBL) is considered as an indolent lymphoma with excellent prognosis, extracutaneous spread and even death due to disseminated disease have been reported. This is a case report of a PCI/MZBL showing dissemination to the regional lymph node and bone marrow, 22 months after the initial diagnosis. Furthermore, in the lymph node, there were focal areas of high-grade transformation. On the other hand, the bone marrow involvement displayed low-grade morphology. We suggest that it should be kept in mind that there is still a possibility of systemic involvement in PCI/MZBL.