Increased DNA damage and oxidative stress in patients with rheumatoid arthritis

ALTINDAG O., KARAKOC M., Kocyigit A., CELIK H., SORAN N.

CLINICAL BIOCHEMISTRY, vol.40, pp.167-171, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40
  • Publication Date: 2007
  • Doi Number: 10.1016/j.clinbiochem.2006.10.006
  • Journal Name: CLINICAL BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.167-171
  • Keywords: rheumatoid arthritis, oxidative stress, DNA damage, TOTAL ANTIOXIDANT CAPACITY, SYNOVIAL-FLUID, FREE-RADICALS, NITRIC-OXIDE, CARCINOGENESIS, PEROXIDATION, INFLAMMATION, DISEASES, CANCER, OXYGEN
  • Bezmialem Vakıf University Affiliated: No

Abstract

Objectives: Oxidative stress has been described as an important mechanism that underlies chronic inflammation in rheumatoid arthritis (RA). The aim of the study was to investigate the peripheral DNA damage, total antioxidant status (TAS), and total oxidative status (TOS) in patients with RA.