Is there a link between pre-existing antibodies acquired due to childhood vaccinations or past infections and COVID-19? A case control study


SÜMBÜL B. , Sumbul H. E. , OKYAY R. A. , Gulumsek E., ŞAHİN A. R. , Boral B., ...More

PEERJ, vol.9, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9
  • Publication Date: 2021
  • Doi Number: 10.7717/peerj.10910
  • Title of Journal : PEERJ

Abstract

Background: There is growing evidence indicating that children are less affected from COVID-19. Some authors speculate that childhood vaccinations may provide some cross-protection against COVID-19. In this study, our aim was to compare the circulating antibody titers for multiple childhood vaccine antigens, as an indicator of the state of immune memory between patients with COVID-19 and healthy controls, with a specific aim to identify the association between disease severity and antibody titrations which may indicate a protective function related to vaccine or disease induced memory.