Is there a link between pre-existing antibodies acquired due to childhood vaccinations or past infections and COVID-19? A case control study

SÜMBÜL B., Sumbul H. E., OKYAY R. A., Gulumsek E., ŞAHİN A. R., Boral B., ...Daha Fazla

PEERJ, cilt.9, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2021
  • Doi Numarası: 10.7717/peerj.10910
  • Dergi Adı: PEERJ
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Background: There is growing evidence indicating that children are less affected from COVID-19. Some authors speculate that childhood vaccinations may provide some cross-protection against COVID-19. In this study, our aim was to compare the circulating antibody titers for multiple childhood vaccine antigens, as an indicator of the state of immune memory between patients with COVID-19 and healthy controls, with a specific aim to identify the association between disease severity and antibody titrations which may indicate a protective function related to vaccine or disease induced memory.